New Step by Step Map For pkrrating
autophosphorylation at T466 just isn't feasible In this particular geometry as well as the docking site on helix αG for the substrate eIF2α is blocked. having said that, comparable interfaces utilizing the αEF and αG helices are already described for trans-autophosphorylation complexes of PAK159 and PknB60. The mechanistic relevance of activat